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HOME > Cold & Flu > Delsym Syrup

Delsym Syrup
(DEXTROMETHORPHAN POLISTIREX)

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Action And Clinical Pharmacology: Dextromethorphan is a centrally acting antitussive which is comparable to codeine on a mg basis for cough suppression but lacking analgesic or addictive properties. Antitussive efficacy in adults is seen after 10 to 20 mg doses every 4 hours or 30 mg every 6 to 8 hours. With the usual therapeutic dosage, no effect has been noted on respiratory, cardiovascular or gastrointestinal function. Respiratory depression has been noted following ingestion of very large doses. Dextromethorphan polistirex is a sustained-release preparation. Clinical bioavailability studies have shown that a single 60 mg dose provides plasma concentrations of dextromethorphan similar to those obtained with two 30 mg doses of dextromethorphan HBr given at 6 hour intervals. After repeated doses at steady state, equivalent plasma concentrations are maintained when Delsym is taken every 12 hours as compared to dextromethorphan HBr every 6 hours. Indications: For the temporary relief of cough due to minor throat and bronchial irritation as may occur with the common cold or with inhaled irritants.

Manufactured by: Novartis Consumer


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